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8FWS:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
PDB ID:
8FWS
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MMDB ID:
229260
PDB Deposition Date:
2023/1/23
Updated in MMDB:
2023/04
Experimental Method:
electron microscopy
Resolution:
3.23 Å
Source Organism:
Rattus norvegicus
Similar Structures:
VAST+
Download sequence data
Biological Unit for 8FWS: tetrameric; determined by author
Molecular Components in 8FWS
Label
Count
Molecule
Proteins (4 molecules)
A
B
C
D
4
Glutamate Receptor Ionotropic, Kainate 2
(Gene symbol:
Grik2
)
Chemicals and Non-standard biopolymers (46 molecules)
1
14
2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
beta-D-mannopyranose
3
4
4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
4
16
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
5
6
SODIUM ION
6
2
CHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303