8FV3: EGFR(T790M/V948R) in complex with compound 1 (LN4503)

PDB ID: 8FV3Download
MMDB ID: 241291
PDB Deposition Date: 2023/1/18
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 8FV3: dimeric; determined by author and by software (PISA)
Molecular Components in 8FV3
Label Count Molecule
Proteins (2 molecules)
2
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303