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8FUI:
HIV-1 wild type protease with GRL-02519A, with N-(2,5-dimethylphenyl)-4-(pyridin-3-yl)pyrimidin-2-amine as P2-P3 group
PDB ID:
8FUI
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MMDB ID:
230569
PDB Deposition Date:
2023/1/17
Updated in MMDB:
2024/05
Experimental Method:
x-ray diffraction
Resolution:
1.25 Å
Source Organism:
Human immunodeficiency virus 1
Similar Structures:
VAST+
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Biological Unit for 8FUI: dimeric; determined by author and by software (PISA)
Molecular Components in 8FUI
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Protease
Chemicals and Non-standard biopolymers (11 molecules)
1
1
N-{(2S,3R)-4-[(4-aminobenzene-1-sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}-4-methyl-3-{[(4P)-4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide
2
2
SODIUM ION
3
4
CHLORIDE ION
4
1
ACETATE ION
5
1
GLYCEROL
6
2
FORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303