8FU3: Structure Of Respiratory Syncytial Virus Polymerase with Novel Non-Nucleoside Inhibitor

PDB ID: 8FU3Download
MMDB ID: 237448
PDB Deposition Date: 2023/1/16
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 2.88  Å
Source Organism:
Similar Structures:
Biological Unit for 8FU3: pentameric; determined by author
Molecular Components in 8FU3
Label Count Molecule
Proteins (5 molecules)
1
RNA-directed RNA Polymerase L
(Gene symbol: DZD21_gp1)
Molecule annotation
4
Phosphoprotein
(Gene symbol: P)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
8-methoxy-3-methyl-N-{(2S)-3,3,3-trifluoro-2-[5-fluoro-6-(4-fluorophenyl)-4-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-hydroxypropyl}cinnoline-6-carboxamide8-methoxy-3-methyl-N-{(2S)-3,3,3-trifluoro-2-[5-fluoro-6-(4-fluorophenyl)-4-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-hydroxypropyl}cinnoline-6-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303