8FTA: Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16

PDB ID: 8FTADownload
MMDB ID: 241665
PDB Deposition Date: 2023/1/11
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 8FTA: monomeric; determined by author
Molecular Components in 8FTA
Label Count Molecule
Protein (1 molecule)
1
Protein Polybromo-1
(Gene symbol: PBRM1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(2S)-5-chloro-2-(3-methylphenyl)-2,3-dihydroquinazolin-4(1H)-one(2S)-5-chloro-2-(3-methylphenyl)-2,3-dihydroquinazolin-4(1H)-one
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303