8FSJ: Cryo-EM structure of engineered hepatitis C virus E1E2 ectodomain in complex with antibodies AR4A, HEPC74, and IGH520

PDB ID: 8FSJDownload
MMDB ID: 233060
PDB Deposition Date: 2023/1/10
Updated in MMDB: 2023/07
Experimental Method:
electron microscopy
Resolution: 3.65  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8FSJ: hexameric; determined by author
Molecular Components in 8FSJ
Label Count Molecule
Proteins (6 molecules)
1
HCV E2 Ectodomain, Synzip2 Scaffold Fusion
Molecule annotation
1
Hepc74 Heavy Chain
Molecule annotation
1
Hepc74 Light Chain
Molecule annotation
1
HCV E1 Ectodomain, Synzip1 Scaffold Fusion
Molecule annotation
1
Ar4a Light Chain
Molecule annotation
1
Ar4a Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
22
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
6
beta-D-mannopyranosebeta-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303