8FRJ: Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946

PDB ID: 8FRJDownload
MMDB ID: 233284
PDB Deposition Date: 2023/1/7
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.57  Å
Source Organism:
Similar Structures:
Biological Unit for 8FRJ: monomeric; determined by author
Molecular Components in 8FRJ
Label Count Molecule
Protein (1 molecule)
1
Transcription Factor Etv6,guanine-n7 Methyltransferase Nsp14 Chimera
(Gene symbol: ETV6)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303