8FOI: Native GABA-A receptor from the mouse brain, alpha1-beta2-gamma2 subtype, in complex with GABA and allopregnanolone

PDB ID: 8FOIDownload
MMDB ID: 235795
PDB Deposition Date: 2022/12/30
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8FOI: nonameric; determined by author
Molecular Components in 8FOI
Label Count Molecule
Proteins (9 molecules)
2
Gamma-aminobutyric Acid Receptor Subunit Alpha-1
Molecule annotation
2
Gamma-aminobutyric Acid Receptor Subunit Beta-2
Molecule annotation
1
Gamma-aminobutyric Acid Receptor Subunit Gamma-2
Molecule annotation
2
Heavy Chain of 8E3 FAB
Molecule annotation
2
Light Chain of 8e3-fab
Molecule annotation
Chemicals and Non-standard biopolymers (81 molecules)
1
15
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
7
beta-D-mannopyranosebeta-D-mannopyranose
3
14
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
5
17
DODECANEDODECANE
6
17
N-OCTANEN-OCTANE
7
5
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
8
2
GAMMA-AMINO-BUTANOIC ACIDGAMMA-AMINO-BUTANOIC ACID
9
2
allopregnanoloneallopregnanolone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303