8FOG: Crystal structure of human DNA polymerase eta incorporating dITP across dT

PDB ID: 8FOGDownload
MMDB ID: 229822
PDB Deposition Date: 2022/12/30
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.29  Å
Source Organism:
Similar Structures:
Biological Unit for 8FOG: trimeric; determined by author and by software (PISA)
Molecular Components in 8FOG
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase ETA
(Gene symbol: POLH)
Molecule annotation
Nucleotides(2 molecules)
1
DNA Template
Molecule annotation
1
DNA Primer
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
2'-deoxyinosine 5'-triphosphate2'-deoxyinosine 5'-triphosphate
2
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303