8FOA: Cryo-EM structure of human TRPV6 in complex with the natural phytoestrogen genistein

PDB ID: 8FOADownload
MMDB ID: 230565
PDB Deposition Date: 2022/12/30
Updated in MMDB: 2024/06
Experimental Method:
electron microscopy
Resolution: 2.66  Å
Source Organism:
Similar Structures:
Biological Unit for 8FOA: tetrameric; determined by author
Molecular Components in 8FOA
Label Count Molecule
Proteins (4 molecules)
4
Transient Receptor Potential Cation Channel Subfamily V Member 6
(Gene symbol: TRPV6)
Molecule annotation
Chemicals and Non-standard biopolymers (53 molecules)
1
12
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
2
36
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
3
2
ZINC IONZINC ION
4
1
CALCIUM IONCALCIUM ION
5
2
GENISTEINGENISTEIN
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303