8FLV: Bruton's tyrosine kinase in complex with compound 34

PDB ID: 8FLVDownload
MMDB ID: 228746
PDB Deposition Date: 2022/12/22
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8FLV: monomeric; determined by author
Molecular Components in 8FLV
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase BTK
(Gene symbol: BTK)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-(3,5-dichloroanilino)-1-{(3R)-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one2-(3,5-dichloroanilino)-1-{(3R)-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one
2
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303