8FKE: Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR32904

PDB ID: 8FKEDownload
MMDB ID: 245334
PDB Deposition Date: 2022/12/21
Updated in MMDB: 2025/05
Experimental Method:
x-ray diffraction
Resolution: 2.02  Å
Source Organism:
Similar Structures:
Biological Unit for 8FKE: dimeric; determined by author and by software (PISA)
Molecular Components in 8FKE
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Gamma
(Gene symbol: PPARG)
Molecule annotation
1
Nuclear Receptor Corepressor 1
(Gene symbol: NCOR1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-chloro-N-(2-methylpyridin-4-yl)-5-nitrobenzamide2-chloro-N-(2-methylpyridin-4-yl)-5-nitrobenzamide
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303