8FJV: Human GAR transformylase in complex with GAR substrate and AGF362 inhibitor

PDB ID: 8FJVDownload
MMDB ID: 235140
PDB Deposition Date: 2022/12/20
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.69  Å
Source Organism:
Similar Structures:
Biological Unit for 8FJV: monomeric; determined by author
Molecular Components in 8FJV
Label Count Molecule
Protein (1 molecule)
1
Trifunctional Purine Biosynthetic Protein Adenosine-3
(Gene symbol: GART)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
GLYCINAMIDE RIBONUCLEOTIDEGLYCINAMIDE RIBONUCLEOTIDE
2
1
N-{4-[4-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)butyl]-3-fluorothiophene-2-carbonyl}-L-glutamic acidN-{4-[4-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)butyl]-3-fluorothiophene-2-carbonyl}-L-glutamic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303