8FFX: Crystal structure of HIV-1 reverse transcriptase in complex with non-nucleoside inhibitor 19980

PDB ID: 8FFXDownload
MMDB ID: 229574
PDB Deposition Date: 2022/12/10
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.42  Å
Source Organism:
Similar Structures:
Biological Unit for 8FFX: dimeric; determined by author and by software (PISA)
Molecular Components in 8FFX
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
1
P51 RT
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
1
ethyl (8S)-4-(cyclopropylethynyl)pyrazolo[1,5-a]pyridine-3-carboxylateethyl (8S)-4-(cyclopropylethynyl)pyrazolo[1,5-a]pyridine-3-carboxylate
3
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303