8FFW: Cryo-EM structure of the GR-Hsp90-FKBP51 complex

PDB ID: 8FFWDownload
MMDB ID: 237440
PDB Deposition Date: 2022/12/10
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 3.23  Å
Source Organism:
Similar Structures:
Biological Unit for 8FFW: tetrameric; determined by author
Molecular Components in 8FFW
Label Count Molecule
Proteins (4 molecules)
2
Heat Shock Protein HSP 90-alpha
(Gene symbol: HSP90AA1)
Molecule annotation
1
Glucocorticoid Receptor
(Gene symbol: NR3C1)
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase Fkbp5
(Gene symbol: FKBP5)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
DEXAMETHASONEDEXAMETHASONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303