8FEC: Structure of J-PKAc chimera complexed with Aplithianine derivative

PDB ID: 8FECDownload
MMDB ID: 236794
PDB Deposition Date: 2022/12/6
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 8FEC: dimeric; determined by author and by software (PISA)
Molecular Components in 8FEC
Label Count Molecule
Proteins (2 molecules)
1
Dnaj Homolog Subfamily B Member 1,camp-dependent Protein Kinase Catalytic Subunit Alpha
(Gene symbol: PRKACA)
Molecule annotation
1
Camp-dependent Protein Kinase Inhibitor Alpha
(Gene symbol: PKIA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-[(6P)-6-(4-bromo-1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7H-purine6-[(6P)-6-(4-bromo-1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7H-purine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303