8FDX: AGF271 and GAR in complex with human recombinant GARFTase, ligase, purine biosynthesis, transfers formyl group from 10-formyl tetrahydrofolate to glycinamide ribonucleotide (GAR) to form tetrahydrofolate and formyl GAR

PDB ID: 8FDXDownload
MMDB ID: 230082
PDB Deposition Date: 2022/12/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.07  Å
Source Organism:
Similar Structures:
Biological Unit for 8FDX: monomeric; determined by author and by software (PISA)
Molecular Components in 8FDX
Label Count Molecule
Protein (1 molecule)
1
Trifunctional Purine Biosynthetic Protein Adenosine-3
(Gene symbol: GART)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
GLYCINAMIDE RIBONUCLEOTIDEGLYCINAMIDE RIBONUCLEOTIDE
2
1
N-{4-[3-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl}-L-glutamic acidN-{4-[3-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl}-L-glutamic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303