8FAE: Asymmetric structure of cleaved HIV-1 AE2 envelope glycoprotein trimer in styrene-maleic acid lipid nanoparticles (AE2.1)

PDB ID: 8FAEDownload
MMDB ID: 231163
PDB Deposition Date: 2022/11/26
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8FAE: hexameric; determined by author
Molecular Components in 8FAE
Label Count Molecule
Proteins (6 molecules)
3
Envelope Glycoprotein Gp41
Molecule annotation
3
Envelope Glycoprotein Gp120
Molecule annotation
Chemicals and Non-standard biopolymers (250 molecules)
1
144
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
51
beta-D-mannopyranosebeta-D-mannopyranose
3
12
alpha-L-fucopyranosealpha-L-fucopyranose
4
40
alpha-D-mannopyranosealpha-D-mannopyranose
5
3
1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303