8F93: WDR5 covalently modified at Y228 by (R)-2-SF

PDB ID: 8F93Download
MMDB ID: 230879
PDB Deposition Date: 2022/11/23
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8F93: dimeric; determined by author and by software (PISA)
Molecular Components in 8F93
Label Count Molecule
Proteins (2 molecules)
2
WD Repeat-containing Protein 5
(Gene symbol: WDR5)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
3-ethynyl-5-{[(3R)-4-{1-[(2-methoxyphenyl)methyl]-1H-benzimidazole-5-carbonyl}-3-methylpiperazin-1-yl]methyl}benzene-1-sulfonyl fluoride3-ethynyl-5-{[(3R)-4-{1-[(2-methoxyphenyl)methyl]-1H-benzimidazole-5-carbonyl}-3-methylpiperazin-1-yl]methyl}benzene-1-sulfonyl fluoride
2
4
GLYCEROLGLYCEROL
3
2
SULFATE IONSULFATE ION
4
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303