8F8E: Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound

PDB ID: 8F8EDownload
MMDB ID: 227352
PDB Deposition Date: 2022/11/21
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 8F8E: monomeric; determined by author
Molecular Components in 8F8E
Label Count Molecule
Protein (1 molecule)
1
Ddb1- and Cul4-associated Factor 1
(Gene symbol: DCAF1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide(3P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303