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8F88:
Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with monophosphorylated JAK2 activation loop phosphopeptide
PDB ID:
8F88
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MMDB ID:
232473
PDB Deposition Date:
2022/11/21
Updated in MMDB:
2024/11
Experimental Method:
x-ray diffraction
Resolution:
3.1 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 8F88: dimeric; determined by author and by software (PISA)
Molecular Components in 8F88
Label
Count
Molecule
Proteins (2 molecules)
A
1
Tyrosine-protein Phosphatase Non-receptor Type 1
(Gene symbol:
PTPN1
)
E
1
Tyrosine-protein Kinase Jak2
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303