8F5S: human branched chain ketoacid dehydrogenase kinase in complex with inhibitors

PDB ID: 8F5SDownload
MMDB ID: 232470
PDB Deposition Date: 2022/11/15
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 2.793  Å
Source Organism:
Similar Structures:
Biological Unit for 8F5S: dimeric; determined by author
Molecular Components in 8F5S
Label Count Molecule
Proteins (2 molecules)
2
[3-methyl-2-oxobutanoate Dehydrogenase [lipoamide]] Kinase, Mitochondrial
(Gene symbol: BCKDK)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
2
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
POTASSIUM IONPOTASSIUM ION
4
2
(2M)-2-[2-(4-methylphenyl)-1,3-thiazol-4-yl]benzoic acid(2M)-2-[2-(4-methylphenyl)-1,3-thiazol-4-yl]benzoic acid
5
8
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303