8F4Y: Crystal Structure of SARS-CoV-2 2'-O-Methyltransferase in Complex with Compound 5a covalently bound to nsp16 and nsp10

PDB ID: 8F4YDownload
MMDB ID: 236789
PDB Deposition Date: 2022/11/11
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.13  Å
Source Organism:
Similar Structures:
Biological Unit for 8F4Y: dimeric; determined by author and by software (PISA)
Molecular Components in 8F4Y
Label Count Molecule
Proteins (2 molecules)
1
2'-o-methyltransferase
Molecule annotation
1
Non-structural Protein 10
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
2
SODIUM IONSODIUM ION
2
1
4-[(E)-2-(2,4-dichlorophenyl)ethenyl]-6-(trifluoromethyl)pyrimidin-2-ol4-[(E)-2-(2,4-dichlorophenyl)ethenyl]-6-(trifluoromethyl)pyrimidin-2-ol
3
3
4-[2-(2,4-dichlorophenyl)ethyl]-6-(trifluoromethyl)pyrimidin-2-ol4-[2-(2,4-dichlorophenyl)ethyl]-6-(trifluoromethyl)pyrimidin-2-ol
4
10
FORMIC ACIDFORMIC ACID
5
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303