8F2S: Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with rocuronium, pore-blocked state

PDB ID: 8F2SDownload
MMDB ID: 231153
PDB Deposition Date: 2022/11/8
Updated in MMDB: 2023/06
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8F2S: pentameric; determined by author
Molecular Components in 8F2S
Label Count Molecule
Proteins (5 molecules)
2
Acetylcholine Receptor Subunit Alpha
Molecule annotation
1
Acetylcholine Receptor Subunit Delta
Molecule annotation
1
Acetylcholine Receptor Subunit Beta
Molecule annotation
1
Acetylcholine Receptor Subunit Gamma
Molecule annotation
Chemicals and Non-standard biopolymers (38 molecules)
1
13
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
beta-D-mannopyranosebeta-D-mannopyranose
3
8
alpha-D-mannopyranosealpha-D-mannopyranose
4
3
rocuroniumrocuronium
5
6
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
6
3
CHOLESTEROLCHOLESTEROL
7
1
nonanenonane
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303