8EWY: Structure of Janus Kinase (JAK) dimer complexed with cytokine receptor intracellular domain

PDB ID: 8EWYDownload
MMDB ID: 227659
PDB Deposition Date: 2022/10/24
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 5.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8EWY: tetrameric; determined by author
Molecular Components in 8EWY
Label Count Molecule
Proteins (4 molecules)
2
Tyrosine-protein Kinase
(Gene symbol: Jak1)
Molecule annotation
2
Interferon Lambda Receptor 1
(Gene symbol: Ifnlr1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
ADENOSINEADENOSINE
2
2
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303