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8ET8:
Cryo-EM structure of the organic cation transporter 1 in complex with verapamil
PDB ID:
8ET8
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MMDB ID:
230868
PDB Deposition Date:
2022/10/16
Updated in MMDB:
2023/08
Experimental Method:
electron microscopy
Resolution:
3.45 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 8ET8: monomeric; determined by author
Molecular Components in 8ET8
Label
Count
Molecule
Protein (1 molecule)
A
1
Oct1
Chemicals and Non-standard biopolymers (3 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
(2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303