8ESV: Structure of human ADAM10-Tspan15 complex bound to 11G2 vFab

PDB ID: 8ESVDownload
MMDB ID: 231685
PDB Deposition Date: 2022/10/14
Updated in MMDB: 2023/09
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8ESV: tetrameric; determined by author
Molecular Components in 8ESV
Label Count Molecule
Proteins (4 molecules)
1
Disintegrin and Metalloproteinase Domain-containing Protein 10
Molecule annotation
1
Tetraspanin-15
Molecule annotation
1
11g2 FAB Heavy Chain
Molecule annotation
1
11g2 FAB Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
alpha-D-mannopyranosealpha-D-mannopyranose
3
1
CALCIUM IONCALCIUM ION
4
1
ZINC IONZINC ION
5
1
4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE
6
2
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303