8EST: REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN

PDB ID: 8ESTDownload
MMDB ID: 3403
PDB Deposition Date: 1990/2/21
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 8EST: monomeric; determined by author and by software (PISA)
Molecular Components in 8EST
Label Count Molecule
Protein (1 molecule)
1
Porcine Pancreatic Elastase
(Gene symbol: CELA1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
SULFATE IONSULFATE ION
2
1
CALCIUM IONCALCIUM ION
3
1
ETHYL-(2-CARBOXY-4-GUANIDINIUM-PHENYL)-CHLOROACETATEETHYL-(2-CARBOXY-4-GUANIDINIUM-PHENYL)-CHLOROACETATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303