8ESM: Human triacylglycerol synthesizing enzyme DGAT1 in complex with T863 inhibitor

PDB ID: 8ESMDownload
MMDB ID: 231151
PDB Deposition Date: 2022/10/14
Updated in MMDB: 2024/06
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8ESM: dimeric; determined by author
Molecular Components in 8ESM
Label Count Molecule
Proteins (2 molecules)
2
Diacylglycerol O-acyltransferase 1
(Gene symbol: DGAT1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
{(1r,4r)-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl}acetic acid{(1r,4r)-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl}acetic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303