8ES8: CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239)

PDB ID: 8ES8Download
MMDB ID: 229809
PDB Deposition Date: 2022/10/13
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 8ES8: undecameric; determined by author
Molecular Components in 8ES8
Label Count Molecule
Proteins (11 molecules)
2
T-cell Surface Glycoprotein CD3 Zeta Chain
(Gene symbol: CD247)
Molecule annotation
1
T-cell Surface Glycoprotein CD3 Delta Chain
(Gene symbol: CD3D)
Molecule annotation
2
T-cell Surface Glycoprotein CD3 Epsilon Chain
(Gene symbol: CD3E)
Molecule annotation
1
T-cell Surface Glycoprotein CD3 Gamma Chain
(Gene symbol: CD3G)
Molecule annotation
1
Pn45545 TCR Alpha Chain
Molecule annotation
1
Pn45545 TCR Beta Chain
Molecule annotation
1
MHC Class I Antigen
Molecule annotation
1
Beta-2-microglobulin
(Gene symbol: B2M)
Molecule annotation
1
Melanoma-associated Antigen 4
(Gene symbol: MAGEA4)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
17
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
1
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303