8EOH: crystal structure of human Cytochrome P450 8B1 in complex with a C12-Pyridine Containing Steroid

PDB ID: 8EOHDownload
MMDB ID: 233582
PDB Deposition Date: 2022/10/3
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 8EOH: monomeric; determined by author and by software (PISA)
Molecular Components in 8EOH
Label Count Molecule
Protein (1 molecule)
1
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
(Gene symbol: CYP8B1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
12-(pyridin-3-yl)-8alpha,10alpha,13alpha,14beta-androsta-4,11-diene-3,17-dione12-(pyridin-3-yl)-8alpha,10alpha,13alpha,14beta-androsta-4,11-diene-3,17-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303