8EME: EGFR(T790M/V948R) in complex with ZNL-0056

PDB ID: 8EMEDownload
MMDB ID: 236770
PDB Deposition Date: 2022/9/27
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.32  Å
Source Organism:
Similar Structures:
Biological Unit for 8EME: dimeric; determined by author and by software (PISA)
Molecular Components in 8EME
Label Count Molecule
Proteins (2 molecules)
2
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{7-methyl-1-[(3S)-1-(prop-2-enoyl)azepan-3-yl]-1H-benzimidazol-2-yl}-5-(prop-2-enamido)thiophene-3-carboxamideN-{7-methyl-1-[(3S)-1-(prop-2-enoyl)azepan-3-yl]-1H-benzimidazol-2-yl}-5-(prop-2-enamido)thiophene-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303