8EKT: CYP51 from Acanthamoeba castellanii in complex with the tetrazole-based IND inhibitor VT-1161(VT1)

PDB ID: 8EKTDownload
MMDB ID: 233581
PDB Deposition Date: 2022/9/21
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 2.29  Å
Source Organism:
Similar Structures:
Biological Unit for 8EKT: monomeric; determined by author
Molecular Components in 8EKT
Label Count Molecule
Protein (1 molecule)
1
Sterol 14a-demethylase
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
(R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol(R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303