8EG6: huCaspase-6 in complex with inhibitor 2a

PDB ID: 8EG6Download
MMDB ID: 230071
PDB Deposition Date: 2022/9/11
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.82  Å
Source Organism:
Similar Structures:
Biological Unit for 8EG6: tetrameric; determined by software (PISA)
Molecular Components in 8EG6
Label Count Molecule
Proteins (4 molecules)
2
Caspase-6 Subunit P18
(Gene symbol: CASP6)
Molecule annotation
2
Caspase-6 Subunit P11
(Gene symbol: CASP6)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
4
CHLORIDE IONCHLORIDE ION
2
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
(3R)-1-(ethanesulfonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxamide(3R)-1-(ethanesulfonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxamide
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303