8EAB: NKG2D complexed with inhibitor 4f

PDB ID: 8EABDownload
MMDB ID: 229798
PDB Deposition Date: 2022/8/28
Updated in MMDB: 2023/05
Experimental Method:
x-ray diffraction
Resolution: 1.44  Å
Source Organism:
Similar Structures:
Biological Unit for 8EAB: dimeric; determined by author and by software (PISA)
Molecular Components in 8EAB
Label Count Molecule
Proteins (2 molecules)
2
Nkg2-d Type II Integral Membrane Protein
(Gene symbol: KLRK1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
2
1
N-[(1S)-2-oxo-1-[3-(trifluoromethyl)phenyl]-2-({4-[4-(trifluoromethyl)phenyl]pyridin-3-yl}amino)ethyl]-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamideN-[(1S)-2-oxo-1-[3-(trifluoromethyl)phenyl]-2-({4-[4-(trifluoromethyl)phenyl]pyridin-3-yl}amino)ethyl]-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303