8EA9: NKG2D complexed with inhibitor 4d

PDB ID: 8EA9Download
MMDB ID: 229796
PDB Deposition Date: 2022/8/28
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.58  Å
Source Organism:
Similar Structures:
Biological Unit for 8EA9: dimeric; determined by author and by software (PISA)
Molecular Components in 8EA9
Label Count Molecule
Proteins (2 molecules)
2
Nkg2-d Type II Integral Membrane Protein
(Gene symbol: KLRK1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
2
1
N-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-(dimethylamino)-2-oxoethyl]-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamideN-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-(dimethylamino)-2-oxoethyl]-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamide
3
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303