8E6R: Human TRPM2 ion channel in 1 mM dADPR

PDB ID: 8E6RDownload
MMDB ID: 250939
PDB Deposition Date: 2022/8/23
Updated in MMDB: 2024/08
Experimental Method:
electron microscopy
Resolution: 5.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8E6R: tetrameric; determined by author
Molecular Components in 8E6R
Label Count Molecule
Proteins (4 molecules)
4
Transient Receptor Potential Cation Channel Subfamily M Member 2
(Gene symbol: TRPM2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
ADENOSINE-5-DIPHOSPHORIBOSEADENOSINE-5-DIPHOSPHORIBOSE
2
4
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303