National Center for
Biotechnology Information

8E3M: E. coli 50S ribosome bound to L-linker solithromycin conjugate

PDB ID:

MMDB ID:

232136

PDB Deposition Date:

2022/8/17

Updated in MMDB:

2023/07

Experimental Method:

electron microscopy

Resolution:

2.25 Å

Source Organism:

Escherichia coli K-12▼

Taxonomy	Molecule
Escherichia coli K-12	P
Escherichia coli	I, J, K, L, M, N, O, Q, R

Similar Structures:

Biological Unit for 8E3M: decameric; determined by author

Molecular Components in 8E3M
Label	Count	Molecule
Proteins (8 molecules)
K	1	50S Ribosomal Protein L2
L	1	50S Ribosomal Protein L15
M	1	50S Ribosomal Protein L4
N	1	50S Ribosomal Protein L3
O	1	50S Ribosomal Protein L13
P	1	50S Ribosomal Protein L22
Q	1	50S Ribosomal Protein L32
R	1	50S Ribosomal Protein L34
Nucleotides(2 molecules)
I	1	50S Ribosomal RNA
J	1	5S Ribosomal RNA
Chemical and Non-standard biopolymers (1 molecule)
1	1	N-acetyl-L-tyrosyl-N-[(3M)-3-(1-{4-[(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-4-ethyl-7-fluoro-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-10-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}dodecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-1(4H)-yl]butyl}-1H-1,2,3-triazol-4-yl)phenyl]-L-methioninamide

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Citing MMDB