8E1O: Crystal structure of hTEAD2 bound to a methoxypyridine lipid pocket binder

PDB ID: 8E1ODownload
MMDB ID: 234204
PDB Deposition Date: 2022/8/10
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 8E1O: monomeric; determined by author
Molecular Components in 8E1O
Label Count Molecule
Protein (1 molecule)
1
Transcriptional Enhancer Factor Tef-4
(Gene symbol: TEAD2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
2
2
5-methoxy-N-({3-[2-(methylamino)-2-oxoethyl]phenyl}methyl)-4-{(E)-2-[trans-4-(trifluoromethyl)cyclohexyl]ethenyl}pyridine-2-carboxamide5-methoxy-N-({3-[2-(methylamino)-2-oxoethyl]phenyl}methyl)-4-{(E)-2-[trans-4-(trifluoromethyl)cyclohexyl]ethenyl}pyridine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303