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8E17:
BRD4-D1 in complex with BET inhibitor
PDB ID:
8E17
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MMDB ID:
228462
PDB Deposition Date:
2022/8/9
Updated in MMDB:
2023/10
Experimental Method:
x-ray diffraction
Resolution:
1.47 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 8E17: monomeric; determined by author
Molecular Components in 8E17
Label
Count
Molecule
Protein (1 molecule)
B
1
Bromodomain-containing Protein 4
(Gene symbol:
BRD4
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(4P,6M)-6-[1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl]-4-[5-(methanesulfonyl)-2-methoxyphenyl]-2-methylisoquinolin-1(2H)-one
2
1
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303