8E07: Crystal structure of HPSE P6 in complex with triose pentosan inhibitor

PDB ID: 8E07Download
MMDB ID: 232779
PDB Deposition Date: 2022/8/8
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8E07: dimeric; determined by author and by software (PISA)
Molecular Components in 8E07
Label Count Molecule
Proteins (2 molecules)
1
Heparanase 50 KDA Subunit
(Gene symbol: HPSE)
Molecule annotation
1
Heparanase 8 KDA Subunit
(Gene symbol: HPSE)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
4
2,3-di-O-sulfo-beta-D-xylopyranose2,3-di-O-sulfo-beta-D-xylopyranose
2
2
2,3,4-tri-O-sulfo-beta-D-xylopyranose2,3,4-tri-O-sulfo-beta-D-xylopyranose
3
1
ACETATE IONACETATE ION
4
5
SULFATE IONSULFATE ION
5
1
AMMONIUM IONAMMONIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303