8DSW: Crystal structure of EGFR kinase domain, Exon20 Insertion FQEA mutant

PDB ID: 8DSWDownload
MMDB ID: 236102
PDB Deposition Date: 2022/7/23
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.39  Å
Source Organism:
Similar Structures:
Biological Unit for 8DSW: monomeric; determined by author and by software
Molecular Components in 8DSW
Label Count Molecule
Protein (1 molecule)
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303