8DO3: Cryo-EM structure of the human Sec61 complex inhibited by eeyarestatin I

PDB ID: 8DO3Download
MMDB ID: 230533
PDB Deposition Date: 2022/7/12
Updated in MMDB: 2023/09
Experimental Method:
electron microscopy
Resolution: 3.22  Å
Source Organism:
Similar Structures:
Biological Unit for 8DO3: trimeric; determined by author
Molecular Components in 8DO3
Label Count Molecule
Proteins (3 molecules)
1
Protein Transport Protein Sec61 Subunit Gamma
(Gene symbol: SEC61G)
Molecule annotation
1
Protein Transport Protein Sec61 Subunit Beta
(Gene symbol: SEC61B)
Molecule annotation
1
Protein Transport Protein Sec61 Subunit Alpha Isoform 1
(Gene symbol: SEC61A1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N'-(4-chlorophenyl)-N-[(4R)-3-(4-chlorophenyl)-5,5-dimethyl-1-(2-{(2E)-2-[(2E)-3-(5-nitrofuran-2-yl)prop-2-en-1-ylidene]hydrazinyl}-2-oxoethyl)-2-oxoimidazolidin-4-yl]-N-hydroxyureaN'-(4-chlorophenyl)-N-[(4R)-3-(4-chlorophenyl)-5,5-dimethyl-1-(2-{(2E)-2-[(2E)-3-(5-nitrofuran-2-yl)prop-2-en-1-ylidene]hydrazinyl}-2-oxoethyl)-2-oxoimidazolidin-4-yl]-N-hydroxyurea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303