8DNZ: Cryo-EM structure of the human Sec61 complex inhibited by apratoxin F

PDB ID: 8DNZDownload
MMDB ID: 230529
PDB Deposition Date: 2022/7/12
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 2.57  Å
Source Organism:
Similar Structures:
Molecular Components in 8DNZ
Label Count Molecule
Proteins (3 molecules)
1
Protein Transport Protein Sec61 Subunit Gamma
(Gene symbol: SEC61G)
Molecule annotation
1
Protein Transport Protein Sec61 Subunit Beta
(Gene symbol: SEC61B)
Molecule annotation
1
Protein Transport Protein Sec61 Subunit Alpha Isoform 1
(Gene symbol: SEC61A1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2E)-3-{(2R,4S)-2-[(2S,3S,5S,7S)-3,7-dihydroxy-5,8,8-trimethylnonan-2-yl]-1,3-thiazolidin-4-yl}-2-methylprop-2-enoic acid(2E)-3-{(2R,4S)-2-[(2S,3S,5S,7S)-3,7-dihydroxy-5,8,8-trimethylnonan-2-yl]-1,3-thiazolidin-4-yl}-2-methylprop-2-enoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303