8DIV: Crystal structure of NavAb I22V as a basis for the human Nav1.7 Inherited Erythromelalgia I136V mutation

PDB ID: 8DIVDownload
MMDB ID: 237086
PDB Deposition Date: 2022/6/29
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.54  Å
Source Organism:
Similar Structures:
Biological Unit for 8DIV: tetrameric; determined by author and by software (PISA)
Molecular Components in 8DIV
Label Count Molecule
Proteins (4 molecules)
4
Ion Transport Protein
Molecule annotation
Chemicals and Non-standard biopolymers (32 molecules)
1
4
beta-D-glucopyranose (Link to PubChem not yet available)beta-D-glucopyranose
2
20
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (Link to PubChem not yet available)1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
3
8
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE (Link to PubChem not yet available)3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303