8DE3: Native serotonin transporter in complex with 15B8 Fab antibody in the presence of cocaine

PDB ID: 8DE3Download
MMDB ID: 232387
PDB Deposition Date: 2022/6/19
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8DE3: trimeric; determined by author
Molecular Components in 8DE3
Label Count Molecule
Proteins (3 molecules)
1
Transporter
Molecule annotation
1
15b8 FAB Heavy Chain Variable Domain
Molecule annotation
1
15b8 FAB Light Chain Variable Domain
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
CHLORIDE IONCHLORIDE ION
3
2
SODIUM IONSODIUM ION
4
1
COCAINECOCAINE
5
2
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
6
1
DODECYL-BETA-D-MALTOSIDEDODECYL-BETA-D-MALTOSIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303