8D96: Human DNA polymerase alpha/primase elongation complex I bound to primer/template

PDB ID: 8D96Download
MMDB ID: 229227
PDB Deposition Date: 2022/6/9
Updated in MMDB: 2024/06
Experimental Method:
electron microscopy
Resolution: 3.35  Å
Source Organism:
Similar Structures:
Biological Unit for 8D96: tetrameric; determined by author
Molecular Components in 8D96
Label Count Molecule
Proteins (2 molecules)
1
DNA Primase Large Subunit
(Gene symbol: PRIM2)
Molecule annotation
1
DNA Polymerase Alpha Catalytic Subunit
(Gene symbol: POLA1)
Molecule annotation
Nucleotide(1 molecule)
1
DNA (5'-d(*ap*tp*ap*ap*tp*gp*gp*tp*cp*gp*tp*gp*cp*cp*gp*cp*cp*ap*ap*tp*ap*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
E
1
DNA/RNA (5'-GTP)-R(P*GP*CP*GP*GP*CP*AP*CP*G)-D(P*AP*CP*C)-3')
1
1
IRON/SULFUR CLUSTERIRON/SULFUR CLUSTER
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303