8D82: Cryo-EM structure of human IL-6 signaling complex in detergent: model containing full extracellular domains

PDB ID: 8D82Download
MMDB ID: 228449
PDB Deposition Date: 2022/6/7
Updated in MMDB: 2023/04
Experimental Method:
electron microscopy
Resolution: 3.22  Å
Source Organism:
Similar Structures:
Biological Unit for 8D82: hexameric; determined by author
Molecular Components in 8D82
Label Count Molecule
Proteins (6 molecules)
2
Soluble Interleukin-6 Receptor Subunit Alpha
(Gene symbol: IL6R)
Molecule annotation
2
Interleukin-6
(Gene symbol: IL6)
Molecule annotation
2
Interleukin-6 Receptor Subunit Beta
(Gene symbol: IL6ST)
Molecule annotation
Chemicals and Non-standard biopolymers (38 molecules)
1
38
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303