8D7E: Cryo-EM structure of human CNTFR alpha in complex with the Fab fragments of two antibodies

PDB ID: 8D7EDownload
MMDB ID: 228446
PDB Deposition Date: 2022/6/7
Updated in MMDB: 2023/04
Experimental Method:
electron microscopy
Resolution: 2.93  Å
Source Organism:
Similar Structures:
Biological Unit for 8D7E: pentameric; determined by author
Molecular Components in 8D7E
Label Count Molecule
Proteins (5 molecules)
1
Ciliary Neurotrophic Factor Receptor Subunit Alpha
(Gene symbol: CNTFR)
Molecule annotation
1
H4h25311p2 Antibody FAB Fragment Light Chain
Molecule annotation
1
H4h25311p2 Antibody FAB Fragment Heavy Chain
Molecule annotation
1
Regn8938 Antibody FAB Fragment Light Chain
Molecule annotation
1
Regn8938 Antibody FAB Fragment Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303