8D74: Cryo-EM structure of human CNTF signaling complex: model containing the interaction core region

PDB ID: 8D74Download
MMDB ID: 228445
PDB Deposition Date: 2022/6/7
Updated in MMDB: 2023/04
Experimental Method:
electron microscopy
Resolution: 3.03  Å
Source Organism:
Similar Structures:
Biological Unit for 8D74: tetrameric; determined by author
Molecular Components in 8D74
Label Count Molecule
Proteins (4 molecules)
1
Interleukin-6 Receptor Subunit Beta
(Gene symbol: IL6ST)
Molecule annotation
1
Ciliary Neurotrophic Factor
(Gene symbol: CNTF)
Molecule annotation
1
Ciliary Neurotrophic Factor Receptor Subunit Alpha
(Gene symbol: CNTFR)
Molecule annotation
1
Leukemia Inhibitory Factor Receptor
(Gene symbol: LIFR)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
18
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303